PLVAP Antibodies

Target Information

Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development. Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium. Note: This description may include information from UniProtKB.

Alternate Names

DIAR10; FELS; Fenestrated endothelial-linked structure protein; fenestrated-endothelial linked structure protein; gp68; MECA-32 antigen; MECA3; MECA32; plasmalemma vesicle associated protein; Plasmalemma vesicle protein 1; Plasmalemma vesicle-associated protein; PLVAP; Plvap; PV-1; PV-1 protein; PV1; Pv1