RALBP1 Antibodies
Target Information
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. Note: This description may include information from UniProtKB.
Alternate Names
76 kDa Ral-interacting protein; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; ralA binding protein 1; RalA-binding protein 1; RALBP1; RBP1; RIP1; RLIP1; RLIP76RALBP1 Antibody Products
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