SEC24B Antibodies

Target Information

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes. Belongs to the SEC23/SEC24 family. SEC24 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

AI605202; MGC48822; Protein transport protein Sec24B; protein transport protein Sec24B; SC24B; SEC2; SEC24; SEC24 (S. cerevisiae) homolog B; SEC24 family, member B (S. cerevisiae); SEC24 homolog B, COPII coat complex component; SEC24 related gene family, member B; Sec24 related gene family, member B; Sec24 related gene family, member B (S. cerevisiae); Sec24-related gene family, member B (S. cerevisiae); SEC24-related protein B; SEC24B; Sec24b; secretory protein 24