SMAD2 Antibodies
Target Information
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. Belongs to the dwarfin/SMAD family. Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
7120426M23Rik; hMAD-2; hSMAD2; JV18; JV18-1; Mad; MAD homolog 2; MAD homolog 2 (Drosophila); Mad protein homolog; Mad-related protein 2; MAD, mothers against decapentaplegic homolog 2; Madh; MADH2; Madh2; MADR2; Madr2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against DPP homolog 2; Sma- and Mad-related protein 2; SMAD 2; SMAD family member 2; Smad-2; SMAD, mothers against DPP homolog 2; SMAD2; Smad2SMAD2 Antibody Products
45 Products- 8828WBH, M, R, MkRecombinant Monoclonal
- 18338WBIFFChIPH, M, RRecombinant Monoclonal
- 68550FH, M, RRecombinant Monoclonal
- 26945FH, M, RRecombinant Monoclonal
- 55607WBIFFELISA+H, M, R, Mk, MiRecombinant Monoclonal
- 56532FH, M, RRecombinant Monoclonal
- 52554WBH, M, R, MkRecombinant Monoclonal
- 12470WBH, M, R, MkRecombinant Monoclonal
- 55041WBH, M, RRecombinant Monoclonal
- 48853ELISA+H, M, R, Mk, MiRecombinant Monoclonal
- 67617FH, M, R, MkRecombinant Monoclonal
- 94610WBIFFH, M, RRecombinant Monoclonal
- 83065WBIFFH, M, R, MkRecombinant Monoclonal
- 81000ELISA+HRecombinant Monoclonal
- 67804FH, M, RRecombinant Monoclonal
- 32423H, M, RRecombinant Monoclonal
- 45612FH, M, R, MkRecombinant Monoclonal
- 34360H, MRecombinant Monoclonal
- 16950H, M, R, MkRecombinant Monoclonal
- 28095ELISA+H, M, R, MkRecombinant Monoclonal
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