SP3 Antibodies
Target Information
Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping. Belongs to the Sp1 C2H2-type zinc-finger protein family. Ubiquitously expressed. 6 alternative splicing and alternative initiation human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
DKFZp686O1631; GC-binding transcription factor Sp3; SP3; Sp3 transcription factor; specificity protein 3; SPR-2; SPR2; Transcription factor Sp3SP3 Antibody Products
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