TNFRSF13B Antibodies

Target Information

Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

1200009E08Rik; CD267; CVID; CVID2; FLJ39942; IGAD2; MGC133214; MGC39952; OTTMUSP00000006011; RYZN; TACI; Taci; TNF receptor superfamily member 13B; TNFRSF13B; Tnfrsf13b; TNFRSF14B; TR13B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; Transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B; tumor necrosis factor receptor superfamily, member 13b