TOLLIP Antibodies
Target Information
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates. Belongs to the tollip family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
4930403G24Rik; 4931428G15Rik; adapter protein; FLJ33531; IL-1RAcPIP; TOLIP; toll interacting protein; Toll-interacting protein; TOLLIP; TollipTOLLIP Antibody Products
2 ProductsWhy CST
Cell Signaling Technology is trusted by the global scientific research community. Our highly cited antibodies offer unrivaled specificity and reproducibility. Learn more about why researchers choose CST:
Contact
Don’t see an antibody for your specific needs? Browse more products, learn more about our services or get in touch with us: