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55813
Hyaluronidase
Buffers & Dyes
Miscellaneous

Hyaluronidase #55813

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Hyaluronidase: Image 1

Product Usage Information

Hyaluronidase has an optimal pH range of 4.5-6.0. It is recommended to reconstitute with a buffer compatible with the intended assay. Vials should be brought to room temperature prior to opening and they should not be opened in humid areas.

Storage

Hyaluronidase is supplied as a lyophilized powder. This product is stable for 12 months when stored at -20ºC, protected from moisture. Once in solution, aliquot to avoid multiple freeze/thaw cycles.

Product Description

Hyaluronidase is a glycoprotein isolated from bovine testes that degrades hyaluronan (HA) polymers (1). This enzyme hydrolyzes the endo-N-acetylhexosaminic bonds of hyaluronic acid, chondroitinsulfuric acid A, and chondroitinsulfuric acid C to tetrasaccharide rich oligosaccharides (2). Studies have shown that hyaluronidases have the potential for clinical utility as both biomarkers and therapeutic targets when looking at a variety of cancers (1). Hyaluronidase is an effective enzyme for tissue dissociation (3,4).
Activity Greater than or equal to 3,000 units per mg dry weightUnit Definition: One unit is based on the change in absorbency (turbidity) at 540 nm of an internal standard assayed concurrently with each lot. Internal standard replaces USP/NF reference no longer available.
CAS 9003-98-9

Limited Uses

Except as otherwise expressly agreed in a writing signed by a legally authorized representative of CST, the following terms apply to Products provided by CST, its affiliates or its distributors. Any Customer's terms and conditions that are in addition to, or different from, those contained herein, unless separately accepted in writing by a legally authorized representative of CST, are rejected and are of no force or effect.

Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale (alone or as a component) or other commercial purpose, requires a separate license from CST. Customer shall (a) not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, (b) not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST's products or services, (c) not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, (d) use the Products solely in accordance with CST's Product Terms of Sale and any applicable documentation, and (e) comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products.

For Research Use Only. Not For Use In Diagnostic Procedures.
Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
To Purchase # 55813S
Product # Size Price
55813S
30 Kunitz unit $ 405