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Render Timestamp: 2024-12-06T11:26:58.690Z
Commit: 224419269841c11382c4555dbee545259bf6c379
XML generation date: 2024-09-20 06:23:04.743
Product last modified at: 2024-09-20T07:04:44.835Z
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Hyaluronidase #55813

    Product Information

    Product Usage Information

    Hyaluronidase contains 30,000 units and has an optimal pH range of 4.5-6.0. It is recommended to reconstitute with a buffer compatible with the intended assay. Vials should be brought to room temperature prior to opening and they should not be opened in humid areas.

    Storage

    Hyaluronidase is supplied as a lyophilized powder. This product is stable for 12 months when stored at -20ºC, protected from moisture. Once in solution, aliquot to avoid multiple freeze/thaw cycles.

    Product Description

    Hyaluronidase is a glycoprotein isolated from bovine testes that degrades hyaluronan (HA) polymers (1). This enzyme hydrolyzes the endo-N-acetylhexosaminic bonds of hyaluronic acid, chondroitinsulfuric acid A, and chondroitinsulfuric acid C to tetrasaccharide rich oligosaccharides (2). Studies have shown that hyaluronidases have the potential for clinical utility as both biomarkers and therapeutic targets when looking at a variety of cancers (1). Hyaluronidase is an effective enzyme for tissue dissociation (3,4).
    Activity Greater than or equal to 3,000 units per mg dry weight

    Unit Definition: One unit is based on the change in absorbency (turbidity) at 540 nm of an internal standard assayed concurrently with each lot. Internal standard replaces USP/NF reference no longer available.

    Source / Purification

    Hyaluronidase is produced from bovine testes. This product is chromatographically purified and dialyzed prior to lyophilization.
    For Research Use Only. Not For Use In Diagnostic Procedures.
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