Human Stromal Cell-derived Factor 1β/CXCL12 (hSDF1β) #5712
Inquiry Info. # 5712
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Product Information
Formulation
Storage
Maintain sterility. Storage at -20°C should be in a manual defrost freezer.
Product Description
| MW (kDa) | 9 |
| Purity | >98% as determined by SDS-PAGE of 6 μg reduced (+) and non-reduced (-) recombinant hSDF1β. All lots are greater than 98% pure. |
| Endotoxin | Less than 0.01 ng endotoxin/1 μg hSDF1β. |
| Activity | The activity of hSDF1β was determined using an NK-92 cell migration assay. The ED50 of each lot is between 0.1-0.3 µg/ml. |
| Molecular Formula | Recombinant hSDF1β has a Met on the amino terminus and has a calculated MW of 8,657. DTT-reduced protein migrates as an 8 kDa polypeptide and non-reduced protein migrates as a 12 kDa polypeptide. The expected amino-terminal MKPVS of recombinant hSDF1β was verified by amino acid sequencing. |
Source / Purification
Background
- Zlotnik, A. and Yoshie, O. (2000) Immunity 12, 121-7.
- Shirozu, M. et al. (1995) Genomics 28, 495-500.
- Tashiro, K. et al. (1993) Science 261, 600-3.
- Roland, J. et al. (2003) Blood 101, 399-406.
- Bleul, C.C. et al. (1996) J Exp Med 184, 1101-9.
- Ma, Q. et al. (1998) Proc Natl Acad Sci U S A 95, 9448-53.
- Nagasawa, T. et al. (1996) Nature 382, 635-8.
- Mirisola, V. et al. (2009) Eur J Cancer 45, 2579-87.
Limited Uses
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