Render Target: STATIC
Render Timestamp: 2024-09-20T10:06:36.199Z
Commit: c4b931215f8ed52e59fa950853eadce9550a8bd5
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PDP - Template Name: Blocking Peptide
PDP - Template ID: *******6db2f4c

Cytochrome c Blocking Peptide #1033

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    Product Information

    Product Usage Information

    Use as a blocking reagent to evaluate the specificity of antibody reactivity in dot blot protocols.

    Storage

    Supplied in 20 mM potassium phosphate (pH 7.0), 50 mM NaCl, 0.1 mM EDTA, 1 mg/ml BSA and 5% glycerol. 1% DMSO. Store at –20°C.

    Product Description

    This peptide is used to block Cytochrome c (136F3) Rabbit mAb #4280 reactivity.

    Quality Control

    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry. The peptide blocks Cytochrome c (136F3) Rabbit mAb #4280 by dot blot.

    Background

    Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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