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AMACR (2A10) Mouse mAb #3207

Filter:
  • WB

    Supporting Data

    REACTIVITY H M
    SENSITIVITY Endogenous
    MW (kDa) 42
    Source/Isotype Mouse IgG2b
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    AMACR (2A10) Mouse mAb detects endogenous levels of total AMACR protein.

    Species Reactivity:

    Human, Mouse

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a purified truncated recombinant human AMACR-His fusion protein.

    Background

    α-Methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives (1). AMACR has been reported to be a biomarker for prostate cancer (2-4). AMACR expression is also related to other types of cancers, such as hepatocellular carcinoma (1), noninvasive bladder cancer (5), colorectal cancer (6), and gastric adenocarcinoma (7).

    Alternate Names

    2-methylacyl-CoA; 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA; Alpha-methylacyl-CoA racemase; amacr; methylacyl-CoA; methylacyl-CoA racemase; racemase

    For Research Use Only. Not for Use in Diagnostic Procedures.
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