Render Target: STATIC
Render Timestamp: 2024-10-11T10:02:52.701Z
Commit: 56767fe525c928647c8401233a175d0d607d385d
XML generation date: 2024-09-30 02:00:01.523
Product last modified at: 2024-10-03T14:15:14.100Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

AMACR (F7T6V) Rabbit mAb #29256

Filter:
  • WB
  • IP
  • IHC

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 42
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:200
    Immunohistochemistry (Paraffin) 1:400 - 1:1600

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    AMACR (F7T6V) Rabbit mAb recognizes endogenous levels of total AMACR protein. Non-specific diffuse staining was observed in human skeletal muscle, breast myoepithelium, and scattered cells in thymus by immunohistochemistry.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human AMACR protein.

    Background

    α-Methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives (1). AMACR has been reported to be a biomarker for prostate cancer (2-4). AMACR expression is also related to other types of cancers, such as hepatocellular carcinoma (1), noninvasive bladder cancer (5), colorectal cancer (6), and gastric adenocarcinoma (7).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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