AP1S1 (F8K5S) Rabbit Monoclonal Antibody #32979
- WB
- IP
Product Specifications
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 18 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
AP1S1 is one of three possible small adaptin subunits capable of being incorporated into the AP-1 heterotetrameric complex. Mutations in AP1S1 contribute to MEDNIK syndrome, which is characterized by a defect in copper metabolism due to aberrant sorting and trafficking of copper pumps ATP7A and ATP7B (4).
Alternate Names
Adapter-related protein complex 1 sigma-1A subunit; Adaptor protein complex AP-1 sigma-1A subunit; Adaptor protein complex AP-1 subunit sigma-1A; adaptor related protein complex 1 sigma 1 subunit; adaptor related protein complex 1 subunit sigma 1; Adaptor-related protein complex 1 subunit sigma-1A; adaptor-related protein complex 1, sigma 1 subunit; AP-1 complex subunit sigma-1A; AP19; AP1S1; CLAPS1; Clathrin assembly protein complex 1 sigma-1A small chain; Clathrin coat assembly protein AP19; clathrin-associated/assembly/adaptor protein, small 1 (19kD); EKV3; FLJ92436; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit; HA1 19 kDa subunit; MEDNIK; Sigma 1a subunit of AP-1 clathrin; Sigma-adaptin 1A; SIGMA1A; sigma1A subunit of AP-1 clathrin adaptor complex; Sigma1A-adaptin; WUGSC:H_DJ0747G18.2
Limited Uses
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