Render Target: STATIC
Render Timestamp: 2025-01-22T14:08:15.202Z
Commit: da7e4f2f0d1aed1f1f8e20e4e2ecab8f33cbd595
XML generation date: 2025-01-07 23:02:13.769
Product last modified at: 2025-01-10T09:00:11.617Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

BTNL9 (F2F8S) Rabbit mAb #71825

Filter:
  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Transfected Only
    MW (kDa) 70
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    BTNL9 (F2F8S) Rabbit mAb recognizes transfected levels of BTNL9 protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu522 of human BTNL9 protein.

    Background

    Butyrophilin-like (BTNL) proteins are part of the immunoglobulin superfamily and are structurally related to B7 proteins that comprise co-stimulatory and co-inhibitory molecules that regulate T cells. Five BTNL family members have been identified in humans, and eight in mice (1). BTNL proteins play an important role in regulating γδT cells, and BTNL-fc fusion proteins and soluble BTNL molecules have been shown to inhibit T cell activation (2,3). The BTNL family member, BTNL9, has been identified as a prognostic marker and possible therapeutic target in multiple malignancies, including uveal melanoma, breast cancer, lung adenocarcinoma (LUAD), and thyroid cancer (4-7).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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