Render Target: STATIC
Render Timestamp: 2024-10-24T10:29:21.028Z
Commit: 56767fe525c928647c8401233a175d0d607d385d
XML generation date: 2024-09-20 06:22:13.239
Product last modified at: 2024-07-03T20:00:08.008Z
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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

CHGA Antibody #60893

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 80
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:50

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    CHGA Antibody recognizes endogenous levels of total CHGA protein.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val252 of human CHGA protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Background

    Chromogranin A (CHGA) and Chromogranin B (CHGB) are members of the chromogranin/secretogranin family of neuroendocrine secretory proteins. They reside in the secretory vesicles of neurons and endocrine cells and are debated to regulate cargo in the secretory pathway (1,2).
    CHGA is also useful as a serological and immunohistological marker for the presence of neuroendocrine tumors (NETs) from various tissue sources (3,4). CHGA may also be useful for the assessment of disease progression (5,6).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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