CXCL6 (E6V8D) Rabbit mAb #73201
- WB
- IF
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 9 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IF-Immunofluorescence
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunofluorescence (Immunocytochemistry) | 1:100 |
Storage
Protocol
Specificity / Sensitivity
CXCL6 (E6V8D) Rabbit mAb recognizes endogenous levels of total CXCL6 protein.
Species Reactivity:
Human
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CXCL6 protein.
Background
C-X-C motif chemokine 6 (CXCL6) is a secreted molecule that belongs to the C-X-C family of chemokines. Research studies have demonstrated that CXCL6 signals through two membrane receptors, CXCR1 and CXCR2, and plays a role in the inflammatory response through its ability to serve as a chemoattractant and activator for neutrophils (1-3). In addition to regulation of the innate immune response via neutrophils, research studies have demonstrated that CXCL6 displays antibacterial properties through disruption of bacteria membrane integrity (3).
Limited Uses
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