Render Target: STATIC
Render Timestamp: 2024-12-11T10:44:14.967Z
Commit: 611277b6de3cd1bb065350b6ef8d63df412b7185
XML generation date: 2024-09-30 01:59:52.290
Product last modified at: 2024-11-15T19:45:07.690Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

DLX1 (E4T1L) Rabbit mAb #96585

Filter:
  • WB
  • IF

    Supporting Data

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 28
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IF-Immunofluorescence 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunofluorescence (Frozen) 1:200 - 1:800
    Immunofluorescence (Immunocytochemistry) 1:400 - 1:1600

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    DLX1 (E4T1L) Rabbit mAb recognizes endogenous levels of total DLX1 protein.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His245 of human DLX1 protein.

    Background

    Homeobox protein DLX-1 (DLX1) is a member of a family of homeobox genes related to the Drosophila distal-less gene. DLX1 is a transcription factor found in the forebrain of the developing mouse embryo, where it contributes to craniofacial development (1-3). DLX1 also plays a critical role in GABAergic neurogenesis and retinal development (4-7). The DNA-binding activity of DLX1 is mediated by its homeodomain, and DLX1 has been shown to bind to genes that promote neuronal migration and repress neurite growth (8,9). DLX1 expression is regulated by various non-coding RNAs in different cancer types (10-12).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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