ENPP6 (E7P2Q) Rabbit mAb #95214
- WB
Supporting Data
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 50 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
ENPP6 (E7P2Q) Rabbit mAb recognizes endogenous levels of total ENPP6 protein.
Species Reactivity:
Human, Mouse, Rat
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro65 of mouse ENPP6 protein.
Background
Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) is a choline-specific glycerophosphodiesterase that belongs to the ENPP family. The seven ENPP family members play different biological roles in nucleotide and phospholipid signaling, bone mineralization, fibrotic diseases, and tumor-associated immune cell infiltration. ENPP6 is GPI-anchored to the plasma membrane and contains a PDE domain (1). This enzyme hydrolyzes polyunsaturated lysophosphatidylcholine (LPC), glycerophosphorylcholine (GPC), or sphingosylphosphorylcholine (SPC) in kidney and brain (2). It can be used as a marker of newly-forming oligodendrocytes in mouse brain (3).
Limited Uses
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