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KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody #77593

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  • WB
  • IHC

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 14
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunohistochemistry (Paraffin) 1:50 - 1:200

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    For a carrier free (BSA and azide free) version of this product see product #29342.

    Protocol

    Specificity / Sensitivity

    KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody recognizes endogenous levels of total KK-LC-1 protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human KK-LC-1 protein.

    Background

    Kita-kyushu lung cancer antigen 1 (KK-LC-1), also known as CT83, is a small cancer-associated protein that was first discovered as a tumor-specific antigen in lung cancer (1). KK-LC-1 expression is restricted to the testis, but its aberrant expression has been observed in lung, gastric, liver, and triple-negative breast cancer (1-6). Although its exact biological function is not completely understood, KK-LC-1 is being targeted in multiple immunotherapies, including T cell receptor-engineered T cells (TCR-Ts) (7).

    Alternate Names

    Cancer/testis antigen 83; chromosome X open reading frame 61; CT83; CXorf61; FLJ20611; FLJ22913; Kita-kyushu lung cancer antigen 1; KK-LC-1; KKLC1

    For Research Use Only. Not for Use in Diagnostic Procedures.
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