Mios (D12C6) Rabbit mAb #13557
- WB
- IP
Inquiry Info. # 13557
Please see our recommended alternatives.
Product Specifications
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 98 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
The mammalian Mios protein contains six amino-terminal WD repeats and a carboxy terminal zinc finger-like domain. The homologous Drosophila missing oocyte (Mio) protein is required for meiotic progression and oocyte cell fate maintenance during development (6).
- Sancak, Y. et al. (2008) Science 320, 1496-501.
- Kim, E. et al. (2008) Nat Cell Biol 10, 935-45.
- Hay, N. and Sonenberg, N. (2004) Genes Dev 18, 1926-45.
- Wullschleger, S. et al. (2006) Cell 124, 471-84.
- Bar-Peled, L. et al. (2013) Science 340, 1100-6.
- Iida, T. and Lilly, M.A. (2004) Development 131, 1029-39.
Alternate Names
FLJ20323; GATOR complex protein MIOS; GATOR2 complex protein MIOS; H_DJ1159O04.1; meiosis regulator for oocyte development; MIO; MIOS; Missing oocyte meiosis regulator homolog; missing oocyte, meiosis regulator, homolog; missing oocyte, meiosis regulator, homolog (Drosophila); Sea4; WD repeat-containing protein mio; WUGSC:H_DJ1159O04.1; Yulink
Limited Uses
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