Render Target: STATIC
Render Timestamp: 2024-12-02T11:17:25.758Z
Commit: cd2fae6ca3f811b1ddb1df24ac291ed56d5d501b
XML generation date: 2024-09-30 01:59:00.009
Product last modified at: 2024-09-30T08:00:39.804Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

NDUFB9 (E7W6K) Rabbit mAb #99235

Filter:
  • WB

    Supporting Data

    REACTIVITY H M
    SENSITIVITY Endogenous
    MW (kDa) 22
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    NDUFB9 (E7W6K) Rabbit mAb recognizes endogenous levels of total NDUFB9 protein.

    Species Reactivity:

    Human, Mouse

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human NDUFB9 protein.

    Background

    NDUFB9 is an accessory subunit in complex I (NADH: ubiquinone oxidoreductase) of the respiratory chain in mitochondria (1). It is shown that a mutation in the NDUFB9 gene leads to reduced NDUFB9 protein levels and lower complex I activity, indicating a role of this mutation in mitochondrial complex I deficiency (2). In addition, research studies using affinity purification and mass spectrometry show that ORF9c of SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) interacts with NDUFB9 in HEK-293T/17 cells when ORF9c is expressed in HEK-293T/17 cells (3).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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