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Perilipin-3 (F8T8T) Rabbit mAb #61336

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  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 49
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    Perilipin-3 (F8T8T) Rabbit mAb recognizes endogenous levels of total perilipin-3 protein. This antibody does not cross-react with perilipin-1, perilipin-2, perilipin-4, or perilipin-5 protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human perilipin-3 protein.

    Background

    Eukaryotic cells store lipids in lipid droplets. These intracellular lipid storage structures are covered by members of the perilipin family of lipid droplet coat proteins. Perilipins establish an interface between stored lipids and the cytosol, and coordinate lipid storage and utilization (1-3). Research studies suggest that perilipin-3 plays a significant role in the biogenesis of lipid droplets (4). In addition, peroxisome proliferator-activated receptor α (PPARα) promotes PLIN3, also known as TIP47, transcription, lipid droplet accumulation, and cell proliferation in prostate cancer (5).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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