Phospho-TNK1 (Tyr277) Antibody #4553
- WB
Inquiry Info. # 4553
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Product Specifications
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 72 TNK1, 58 TNK1-C17orf61 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Phosphorylation of TNK1 on Tyr277 was identified at Cell Signaling Technology (CST) using PhosphoScan®, CST's LC-MS/MS platform for phosphorylation site discovery (4) and also reported independently in another publication using MS technology (5). Phosphorylation of TNK1 at Tyr277 was observed in select carcinoma cell lines and in tumors. A constitutively active, truncated TNK1 kinase resulting from fusion between the TNK1 and C17orf61 genes is seen in some cells (5). For additional information visit PhosphoSitePlus™, CST's modification site knowledgebase, at www.phosphosite.org.
Alternate Names
CD38 negative kinase 1; KOS1; MGC46193; Non-receptor tyrosine-protein kinase TNK1; TNK1; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor, 1
Limited Uses
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