Render Target: STATIC
Render Timestamp: 2025-03-14T10:36:03.557Z
Commit: a619ae74f66dae0f27639e88da12bcf600e46428
XML generation date: 2025-03-07 13:12:37.832
Product last modified at: 2025-02-11T14:30:15.372Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

RAI2 (D4W9P) Rabbit mAb #97857

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 78
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:50

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    RAI2 (D4W9P) Rabbit mAb recognizes endogenous levels of total RAI2 protein.

    Species Reactivity:

    Human

    The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.

    Species predicted to react based on 100% sequence homology:

    Mouse, Rat, Bovine, Pig

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg522 of human RAI2 protein.

    Background

    Retinoic acid-induced protein 2 (RAI2) is a 530 amino acid protein, encoded by the RAI2 gene on XP22.3 (1). RAI2 contains a central, proline-rich domain that is hypothesized to play a role in protein-protein interactions, and is expressed in a variety of embryonic and adult tissues (2). Beyond that, little is known about the biological functions of RAI2. Notably, a 2015 research study reported that suppressing RAI2 led to increased hematogenous dissemination of breast cancer cells to bone marrow, suggesting that RAI2 may function to negatively regulate tumor metastasis (3).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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