Render Target: STATIC
Render Timestamp: 2024-12-13T10:59:11.933Z
Commit: 611277b6de3cd1bb065350b6ef8d63df412b7185
XML generation date: 2024-09-30 01:59:15.079
Product last modified at: 2024-10-23T13:00:11.701Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

TAPBPR (E5P1F) Rabbit mAb #42383

Filter:
  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 57
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    TAPBPR (E5P1F) Rabbit mAb recognizes endogenous levels of total TAPBPR protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with human TAPBPR recombinant protein.

    Background

    TAPBPR (Tapasin-related protein, TAPBPL) is a type I transmembrane protein expressed primarily in the endoplasmic reticulum (ER) and Golgi apparatus of T cells, B cells, monocytes, and dendritic cells (1,5). TAPBPR acts as a molecular chaperone for major histocompatibility complex class I (MHC class I) and plays a role in the MHC class I-restricted antigen processing and presentation pathway (2-4). TAPBPL has also been described as a novel T cell co-inhibitory molecule and shares both sequence and structural similarities with existing B7 family members of the Ig superfamily (5).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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