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9319
Tyrosinase (T311) Mouse mAb (IHC Specific)

Tyrosinase (T311) Mouse mAb (IHC Specific) #9319

This product is discontinued

Storage:

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Tyrosinase (T311) Mouse mAb detects endogenous levels of total tyrosinase protein.

Tyrosinase (T311) Mouse mAb is produced by immunizing animals with a purified recombinant tyrosinase.

Tyrosinase, found in the membrane of melanosomes (1), is a key enzyme in the biosynthesis of melanin pigments (1,2). It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas (1,3). Tyrosinase is implicated to be an antigen target for melanoma vaccines (1).

  1. Chen, Y.T. et al. (1995) Proc Natl Acad Sci USA 92, 8125-9.
  2. Kwon, B.S. (1993) J Invest Dermatol 100, 134S-140S.
  3. Kwon, B.S. et al. (1987) Proc Natl Acad Sci USA 84, 7473-7.
Entrez-Gene Id
7299
Swiss-Prot Acc.
P14679
For Research Use Only. Not For Use In Diagnostic Procedures.

Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.

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