Basket Updated
0
Items added
Melanomas account for 90% of skin cancer deaths. A big contributor to this: the lack of effective, durable treatments for unresectable, metastatic melanoma.
Learn about host-based and dye-conjugated methods for IF multiplexing, as well as a sequential labeling strategy that works with indirect detection.
A scientific resource for the GEL protein domain containing information on structure, function, and domain binding to actin in cytoskeletal regulation.
Therapeutic developments in treating Alzheimer’s, novel diagnostic tools, and new insights into neurodegeneration mechanisms were key topics at AD/PD 2023.
The chromatin immunoprecipitation (ChIP) assay is a powerful and versatile technique to probe protein-DNA interactions within the natural chromatin context of the cell.
A scientific resource for the FHA protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
A scientific resource for the GAT protein domain containing information on structure, function, and domain binding to ubiquitin and GTP-bound ARF.
Cancer cells adapt mechanisms to evade death by hijacking mechanisms of immune checkpoint control and modulation of the innate immune response via STING.
CST donated $500K to global nonprofits that protect our climate, food, land, water, and wildlife as part of our ongoing commitment to sustainability.
Loading controls are essential to ensure data reliability in your western blot. Learn about the three main considerations for loading control selection.
Use these quick reference tables to determine compatible fluorophore combinations for flow cytometry experiments using parallel or co-linear excitation.
Cell states can be monitored using markers correlating to your process of interest. These assays and antibodies can be used to detect cell viability, senescence, proliferation, apoptosis, cytotoxicity and oxidative state.
6-Phosphate Dehydrogenase (G6PD) Activity Assay Kit #12581; easy to follow directions describing the step by step experimental procedure.
A scientific resource for the Chromo protein domain containing information on structure, function, and binding to methylated lysine residues during chromatin remodeling.
Monoclonal antibodies developed and validated by CST can enable co-detection and spatial characterization of important immune checkpoint control proteins using mIHC
A scientific resource for the CARD protein domain containing information on structure, function, and domain binding during apoptosis.
A multiple antibody strategy is a powerful approach to antibody validation. This provides confidence that antibodies are binding the correct biomolecule.
A scientific resource for the CALM protein domain, also known as ANTH domain, containing information on structure, function, and binding to phospholipids.
A troubleshooting guide for CUT&Tag–a ChIP-seq alternative with lower sample requirements, lower sequencing cost, and improved signal-to-noise for profiling chromatin and protein-DNA interactions.
Flow Cytometry Protocol for FoxP3 on Murine Splenocyte T Cells: easy to follow directions describing the step by step experimental procedure.
PTMScan videos and links to complementary technologies for phospho-peptide enrichment and Science Webinar on Proteomics and Cell Signaling.
Flow Cytometry (F) Protocol for the Detection of Transcription Factors with recommended companion products.
A scientific resource for the EH protein domain containing information on structure, function, and domain binding during endocytosis and vesicle trafficking.
Reggie Prioli, Associate Director of Conjugation at CST®, has been conjugating antibodies at CST since 2001. Let’s find out why!
A scientific resource for the EVH1 protein domain containing information on structure, function, and binding to a proline-rich motif to regulate actin dynamics.
We've hit on every aspect of grant writing in these blogs. You may now be wondering: what are my chances? Am I likely to get funded? We dig into the data.
Senescence has been linked to a general decline in tissue function during aging as well as a number of disease states.
A scientific resource for the WD40 protein domain containing information on structure, function, and binding to both phospho-Ser/Thr and methylated lysine residues.
Learn how enzymatic digestion can help you get better ChIP results.
The adaptive immune response uses antigen-specific receptors to detect foreign antigens with help from T cells, B cells, and NK T cells.