Do any of your MMP-2 antibodies detect active MMP-2?

All four of our MMP-2 antibodies should detect both the full-length proenzyme that runs at 72 kDa and the cleaved, active enzyme that runs at 64 kDa. As the activated form is secreted, it is more difficult to detect using endogenous models and often the 72 kDa proenzyme is more easily detected. In very high expression cell lines, such as U-87 MG, SF-296, and 3T3, the active form can be detected as a faint signal.

Last updated: September 12, 2024