Do your COX IV antibodies detect both isoforms of COX IV?

The antigens for our COX IV Antibody #4844 and COX IV (3E11) Rabbit mAb #4850 are 100% conserved with COX IV isoform 1. There is less than 20% homology of these antigens with COX IV isoform 2, therefore we do not expect these antibodies to detect isoform 2.
The antigen for our COX IV (4D11-B3-E8) Mouse mAb #11967 is also 100% conserved with COX IV isoform 1.  However, the antigen used to produce #11967 is 79% homologous with COX IV isoform 2. Therefore there may be cross-reactivity of this antibody with isoform 2, but we have not tested this in-house and cannot guarantee it.
 

Last updated: September 12, 2024