Does FoxP3/Transcription Factor Fixation/Permeabilization Kit #43481 permeabilize into the nucleus of cells?

Yes, the FoxP3/Transcription Factor Fixation/Permeabilization Kit #43481 is designed to permeabilize cells, including the nuclear membrane. It uses a proprietary Fix/Perm buffer and Perm Wash buffer for this purpose. This kit has been shown to outperform previous protocols that used 2% formaldehyde and 0.3% Triton-X for permeabilization when tested with FoxP3 (D6O8R) Rabbit mAb #12653.

Last updated: August 8, 2025