Does the SARS-CoV-2 Spike Protein Serological IgG ELISA Kit #20154 utilize full-length spike protein?

The recombinant protein utilized by the SARS-CoV-2 Spike Protein Serological IgG ELISA Kit #20154 consists of the complete ectodomain, including all of S1 and S2 of the spike protein. It is not the full-length spike protein but rather the complete ectodomain, which is the domain of a membrane protein that extends into the extracellular space. The ectodomain is usually the part of a protein that initiates contact with surfaces and leads to signal transduction. In SARS-CoV-2, the ectodomain of the spike protein is responsible for attachment to and entry into cells during infection.

Last updated: February 27, 2024