How do the Phospho-Tyrosine Mouse mAb (P-Tyr-100) #9411 and the Phospho-Tyrosine (P-Tyr-1000) MultiMab™ Rabbit mAb mix #8954 compare in terms of their sensitivity and specificity?

The Phospho-Tyrosine Mouse mAb (P-Tyr-100) #9411 is a mouse mAb from a single clone, whereas the Phospho-Tyrosine (P-Tyr-1000) MultiMab™ Rabbit mAb mix #8954 is a mix of rabbit mAbs from multiple clones. The p-Tyr designations, including “p-Tyr-100” and “p-Tyr-1000,” are a naming convention to allow customers to readily differentiate between the multiple products that we offer against this motif. The designations are not meant to suggest differences in quality or performance.  

In general, #8954 is a stronger antibody compared to #9411, and using our PTMScan® technology, we have found that #8954 detects more unique phosphorylated peptides than #9411. Both products are highly specific to phosphorylated tyrosine residues.

 

Last updated: September 12, 2024