What are the high molecular weight bands detected by the β1-Adrenergic Receptor Antibody #12271?

The antigen for the β1-Adrenergic Receptor Antibody #12271 surrounds Gly406 of the human β1-Adrenergic Receptor protein and is contained entirely in the cytoplasmic domain. #12271 detects full-length β1-Adrenergic Receptor as shown on the datasheet (see western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing full-length human β1-Adrenergic Receptor (β1AR; +). The smeary bands that can be observed above 50 kD are a result of N-glycosylation. We have not looked into the issue for further details.

Last updated: March 20, 2024