Why am I seeing a 32 kDa band with the β-Actin Antibody #4967?

β-Actin can be cleaved by caspase-3 between Asp244 and Gly245, which will result in a 32kDa fragment and a 15kDa fragment. Due to the location of its antigen, our β-Actin Antibody #4967 will detect both full-length β-Actin as well as the 32kDa fragment, also known as fractin.

Last updated: September 12, 2024