Render Target: SSR
Render Timestamp: 2024-12-05T16:44:22.922Z
Commit: 224419269841c11382c4555dbee545259bf6c379
Cell Signaling Technology Logo
1% for the planet logo
< Back to Support Article Search Results

Why do your PDGF Receptor α antibodies detect two bands?

PDGF Receptor α (PDGFRa) contains a signal peptide consisting of the first 23 amino acids of the protein sequence. Mature PDGFRa does not contain this signal peptide and it is possible to see a doublet representing both forms; the lower form being the mature protein. This protein is also heavily glycosylated and thus the apparent molecular weight exceeds that of the predicted molecular weight based on amino acid sequence.

Last updated: September 12, 2024

Was this article helpful?

Technical Support

Email: [email protected]

Send Us a Message

Call: 877-678-8324

Customer Support

Email: [email protected]

Send Us a Message

Call: 877-616-2355

Fax: 866-432-6112

Contact Sales

Email: [email protected]

Send Us a Message

Call: 877-616-2355