No More (Data) Secrets: Unlock the Molecular Mechanisms of Pathogenic and Non-Pathogenic Th17 Cells

Single-cell analysis (SCA) continues to increase in popularity due to technological advancements and its ability to identify hard-to-detect cells, reveal cellular heterogeneity, and show how individual cells interact with their environments. While most SCA techniques detect RNA and surface proteins, they are incapable of concurrently measuring intracellular proteins and post-translational modifications, resulting in a truncated view of cellular processes and disease mechanisms. To unlock biological insights more efficiently, researchers “seq” to extract more comprehensive data from the same experiment without additional experiments or validation of results. InTraSeq™ Single Cell Analysis developed by CST enables co-quantification of RNA, both surface and intracellular proteins, and post-translational modifications at a single-cell resolution—in one experiment. Integrating transcriptomic, proteomic, and intracellular interaction data enables more comprehensive analysis to scale our understanding of cellular processes.

Learn how InTraSeq empowers single-cell and translational researchers to:

• Detect RNA, intracellular, and cell surface proteins in thousands of cells simultaneously while guaranteeing robust RNA signal.
• Investigate intracellular signaling pathways together with the transcriptome at the single-cell resolution.
• Identify hard-to-detect cells with an unbiased depth of coverage.
• Explore molecular mechanisms of pathogenic and non-pathogenic Th17 cells in one, streamlined experiment.

For more, visit the InTraSeq Single Cell Analysis Resource Center.

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