Product Pathways - Neuroscience
Neurogenin 2 (D2R3D) Rabbit mAb #13144
|13144S||100 µl (10 western blots)||---||In Stock||---|
|13144||carrier free and custom formulation / quantity||email request|
Already purchased this product? Write a Review.
|W||1:1000||Human, Mouse, Rat||Endogenous||35||Rabbit IgG|
Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IF-F=Immunofluorescence (Frozen)
Specificity / Sensitivity
Neurogenin 2 (D2R3D) Rabbit mAb recognizes endogenous levels of total neurogenin 2 protein.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human neurogenin 2 protein.
Western blot analysis of mouse brain and fetal rat brain using Neurogenin 2 (D2R3D) Rabbit mAb.
Neurogenin 2 (Ngn2, NeuroG2) is a proneural, basic helix-loop-helix transcription (bHLH) factor and member of the neurogenin family that includes neurogenin 1 and neurogenin 3 (1). Neurogenin 2 is expressed in neuronal progenitor cells, is required for generation of glutamatergic neurons and is commonly used as a marker of neuronal differentiation (2,3). Neurogenin 2 upregulates a number of targets including the bHLH transcription factor NeuroD (4). Phosphorylation of Ngn2 at Tyr241 controls migration and dendritic morphology of cortical neurons (5).
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know!
- 7071 Phototope®-HRP Western Blot Detection System, Anti-rabbit IgG, HRP-linked Antibody
- 7074 Anti-rabbit IgG, HRP-linked Antibody
- 7075 Anti-biotin, HRP-linked Antibody
- 7720 Prestained Protein Marker, Broad Range (Premixed Format)
- 7727 Biotinylated Protein Ladder Detection Pack
- 7003 20X LumiGLO® Reagent and 20X Peroxide
- 9997 Tris Buffered Saline with Tween® 20 (TBST-10X)
- 9998 BSA
- 9999 Nonfat Dry Milk
For Research Use Only. Not For Use In Diagnostic Procedures.
DRAQ5® is a registered trademark of Biostatus Limited.
Tween® is a registered trademark of ICI Americas, Inc.
Cell Signaling Technology® is a trademark of Cell Signaling Technology, Inc.