Phospho-RSK2 (Ser227) (D53A11) Rabbit Monoclonal Antibody #3556
- WB
Product Specifications
| REACTIVITY | H M R Mk |
| SENSITIVITY | Endogenous |
| MW (kDa) | 90 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
- Mk-Monkey
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
PDK1 phosphorylates Ser227 in the activation loop of the amino-terminal kinase domain of RSK2, leading to substantial activation of the kinase in vitro and in vivo. The constitutively active PDK1 cooperates with ERK in the activation of RSK following the exposure of cells to growth factors or UV-light (4, 5).
Alternate Names
90 kDa ribosomal protein S6 kinase 1; 90 kDa ribosomal protein S6 kinase 3; CLS; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); epididymis secretory sperm binding protein; HU-1; HU-3; Insulin-stimulated protein kinase 1; ISPK-1; ISPK1; KS6A1; KS6A3; MAP kinase-activated protein kinase 1a; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1a; MAPK-activated protein kinase 1b; MAPKAP kinase 1a; MAPKAP kinase 1b; MAPKAPK-1a; MAPKAPK-1b; MAPKAPK1; MAPKAPK1A; MAPKAPK1B; mental retardation, X-linked 19; MRX19; p90-RSK 1; p90-RSK 3; p90-RSK2; p90RSK; p90RSK1; p90RSK3; p90S6K; pp90RSK2; ribosomal protein S6 kinase A1; ribosomal protein S6 kinase A3; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 3; Ribosomal S6 kinase 1; Ribosomal S6 kinase 2; RPS6KA1; RPS6KA3; RSK; RSK-1; RSK-2; RSK1; RSK2; S6K-alpha 1; S6K-alpha-1; S6K-alpha-3; S6K-alpha3
Limited Uses
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