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CHGA (5H7) Mouse Monoclonal Antibody #36468

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  • IHC

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa)
    Source/Isotype Mouse IgG1
    Application Key:
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    IHC Leica Bond 1:100 - 1:400
    Immunohistochemistry (Paraffin) 1:100 - 1:400

    Storage

    Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 12 months when stored at 4°C. Do not aliquot the antibody.

    Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation.

    Protocol

    Specificity / Sensitivity

    CHGA (5H7) Mouse Monoclonal Antibody recognizes endogenous levels of CHGA protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a prokaryotic recombinant fusion protein corresponding to part of the central region of CHGA protein.

    Background

    Chromogranin A (CHGA) and Chromogranin B (CHGB) are members of the chromogranin/secretogranin family of neuroendocrine secretory proteins. They reside in the secretory vesicles of neurons and endocrine cells and are debated to regulate cargo in the secretory pathway (1,2).CHGA is also useful as a serological and immunohistological marker for the presence of neuroendocrine tumors (NETs) from various tissue sources (3,4). CHGA may also be useful for the assessment of disease progression (5,6).

    Alternate Names

    AL-11; betagranin (N-terminal fragment of chromogranin A); Catestatin; CgA; CHGA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); Chromogranin-A; CMGA; EA-92; ER-37; ES-43; GE-25; GR-44; GV-19; LF-19; p-Glu serpinin precursor; Pancreastatin; parathyroid secretory protein 1; Pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14

    For Research Use Only. Not for Use in Diagnostic Procedures.
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