Osteocalcin (E8B9X) Rabbit Monoclonal Antibody (BSA and Azide Free) #40387
- WB
- IHC
Product Specifications
| REACTIVITY | H |
| SENSITIVITY | |
| MW (kDa) | 12 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IHC-Immunohistochemistry
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.
BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
Formulation
For standard formulation of this product see product #59757
Storage
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Osteocalcin also acts as a hormone that communicates between bone tissue and other organs, such as the pancreas and adipose tissue. It has been implicated in influencing insulin sensitivity and glucose metabolism. Studies suggest that osteocalcin might have a role in improving insulin secretion and reducing insulin resistance. Through downstream effects from its role in insulin signaling, it has been reported to affect a myriad of physiological functions, including male fertility, the acute stress response, exercise, adrenal steroidogenesis, and blood pressure, among other functions. The many studies of osteocalcin have contributed to the model of bone being an endocrine organ, not just a structural component of the skeleton (2).
Alternate Names
BGLAP; BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate protein; Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; OC; OCN; OSTCN; Osteocalcin; PMF1
Limited Uses
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