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DOCK2 (E7X1P) Rabbit Monoclonal Antibody #49392

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  • WB
  • IP

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 200
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:200

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    DOCK2 (E7X1P) Rabbit Monoclonal Antibody recognizes endogenous levels of total DOCK2 protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human DOCK2 protein.

    Background

    DOCK2 (dedicator of cytokinesis 2) is a member of the DOCK-A subfamily of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins (1,3). Expressed in leukocytes, DOCK2 activates isoforms of Rac which regulate chemotaxis as part of the immune response (1,2,4).

    Alternate Names

    dedicator of cyto-kinesis 2; dedicator of cytokinesis 2; Dedicator of cytokinesis protein 2; DOCK2; FLJ46592; IMD40; KIAA0209

    For Research Use Only. Not for Use in Diagnostic Procedures.
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