Render Target: STATIC
Render Timestamp:
5/20/2026, 7:25:12 AM EDT
5/20/2026, 11:25:12 AM UTC
Commit: 7ed46ecc04b401f23a28df741b5078df405d23e4
XML generation date: 2026-05-20 06:50:44.906
Product last modified at: 2026-05-20T08:00:12.892Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
  1. Products /
  2. Primary Antibodies /
  3. Pan-TEAD (D3F7L) Rabbit Monoclonal Antibody (BSA and Azide Free)
Recombinant Flag
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

Pan-TEAD (D3F7L) Rabbit Monoclonal Antibody (BSA and Azide Free) #60062

Filter:
  • WB

    Product Specifications

    REACTIVITY H M R Mk
    SENSITIVITY Endogenous
    MW (kDa) 50, 53, 55, 60
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 
    • Mk-Monkey 

    Product Information

    Product Usage Information

    This product is the carrier free version of product #13295. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.

    This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.

    BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.

    Formulation

    Supplied in 1X PBS (10 mM Na2HPO4, 3 mM KCl, 2 mM KH2PO4, and 140 mM NaCl (pH 7.8)). BSA and Azide Free.

    For standard formulation of this product see product #13295

    Storage

    Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.

    Specificity / Sensitivity

    Pan-TEAD (D3F7L) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total TEAD proteins. This antibody has been shown to recognize TEAD 1, 2, 3 and 4 in transfected cell extracts.

    Species Reactivity:

    Human, Mouse, Rat, Monkey

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys65 of human TEAD1 protein.

    Background

    The Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis (1,2). An integral function of the Hippo pathway is to repress the activity of Yes-associated protein (YAP), a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization (3,4). When the Hippo pathway is turned on, YAP is phosphorylated by LATS1/2 kinase and sequestered in the cytoplasm by 14-3-3 protein binding, rendering YAP inactive. When the Hippo pathway is off, non-phosphorylated YAP translocates to the nucleus where it associates with various transcription factors including members of the transcriptional enhancer factor (TEF) family, also known as the TEA domain (TEAD) family (TEAD1-4) (5,6). Although widely expressed in tissues, the TEAD family proteins have specific tissue and developmental distributions. YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis (5).

    Alternate Names

    AA; atrophia areata, peripapillary chorioretinal degeneration; DTEF-1; EFTR-2; ETF; ETFR-1; hRTEF-1B; MGC9014; NTEF-1; Protein GT-IIC; REF1; related transcription enhancer factor 1B; RTEF1; SV40 transcriptional enhancer factor; TCF-13; TCF13; TCF13L1; TEA domain family member 1; TEA domain family member 1 (SV40 transcriptional enhancer factor); TEA domain family member 2; TEA domain family member 3; TEA domain family member 4; TEA domain family member 5; TEA domain transcription factor 1; TEA domain transcription factor 2; TEA domain transcription factor 3; TEA domain transcription factor 4; TEAD-1; TEAD-2; TEAD-3; TEAD-4; TEAD1; TEAD2; TEAD3; TEAD4; TEAD5; TEF-1; TEF-3; TEF-4; TEF-5; TEF1; TEF3; TEF4; TEF5; TEFR-1; Transcription factor 13; Transcription factor 13-like 1; Transcription factor RTEF-1; transcriptional enhancer factor 1; transcriptional enhancer factor 1-related; transcriptional enhancer factor 3; transcriptional enhancer factor 5; Transcriptional enhancer factor TEF-1; Transcriptional enhancer factor TEF-3; Transcriptional enhancer factor TEF-4; Transcriptional enhancer factor TEF-5; Transcriptional enhancer factor TEF-5 (DTEF-1)

    Database Links

    UniProt ID: Q15562 , P28347 , Q15561 , Q99594


    Entrez-Gene Id: 8463 , 7003 , 7004 , 7005


    Limited Uses

    Except as otherwise expressly agreed in a writing signed by a legally authorized representative of CST, the following terms apply to Products provided by CST, its affiliates or its distributors. Any Customer's terms and conditions that are in addition to, or different from, those contained herein, unless separately accepted in writing by a legally authorized representative of CST, are rejected and are of no force or effect.

    Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale (alone or as a component) or other commercial purpose, requires a separate license from CST. Customer shall (a) not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, (b) not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST products or services, (c) not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, (d) use the Products solely in accordance with CST Product Terms of Sale and any applicable documentation, and (e) comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products.

    For Research Use Only. Not for Use in Diagnostic Procedures.
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