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CD200 (F6V8L) Rabbit Monoclonal Antibody #62325

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  • WB
  • IF

    Product Specifications

    REACTIVITY M R
    SENSITIVITY Endogenous
    MW (kDa) 45-60
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IF-Immunofluorescence 
    Species Cross-Reactivity Key:
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunofluorescence (Frozen) 1:200 - 1:800

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    CD200 (F6V8L) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD200 protein.

    Species Reactivity:

    Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of mouse CD200 protein.

    Background

    CD200 (OX2) and CD200R (OX2R) are membrane glycoprotein members of the Ig superfamily (1-3). CD200 is expressed by a range of cells, including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells, while its receptor, CD200R, is found on myeloid and T cells (1-5). Interaction between CD200 and CD200R downregulates macrophage function and plays a role in immunosuppression and regulation of anti-tumor immune responses (3-7).

    Alternate Names

    antigen identified by monoclonal antibody MRC OX-2; Cd200; CD200 antigen; Mox; Mox2; MRC OX-2 antigen; OX-2 membrane glycoprotein; OX2; OX2G

    For Research Use Only. Not for Use in Diagnostic Procedures.
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