VGAT (F8M4M) Rabbit Monoclonal Antibody #77460
- WB
- IF
Product Specifications
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 57 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IF-Immunofluorescence
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunofluorescence (Frozen) | 1:100 - 1:400 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Recently, tau accumulation, as found in Alzheimer’s disease (AD) patients, has been shown to selectively suppress the expression of the intracellular VGAT (3). At the same time, VGAT activation can help with anxiety exacerbated by AD pathology (4).
Alternate Names
GABA and glycine transporter; hVIAAT; SLC32A1; solute carrier family 32 (GABA vesicular transporter), member 1; Solute carrier family 32 member 1; solute carrier family 32, member 1; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT
Limited Uses
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