Phospho-BCL2L13 (Ser261) Antibody #82971
- WB
Product Specifications
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 90 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Phosphorylation of BCL2L13 at Ser275 plays a role in the clearance of damaged mitochondria through mitophagy and is important in maintaining cardiac function (7). Phosphorylation of BCL2L13 at Ser261 and Ser275 occurs following AMPK activation. For more information, visit BioRxiv at https://www.biorxiv.org/content/10.1101/2025.07.10.663832v1.
- Kataoka, T. et al. (2001) J Biol Chem 276, 19548-54.
- Kataoka, T. (2022) Front Cell Dev Biol 10, 1065702.
- Kim, J.Y. et al. (2012) FEBS Lett 586, 3142-9.
- Jensen, S.A. et al. (2014) Proc Natl Acad Sci USA 111, 5682-7.
- Murakawa, T. et al. (2015) Nat Commun 6, 7527.
- Otsu, K. et al. (2015) Autophagy 11, 1932-3.
- Murakawa, T. et al. (2024) Cell Rep 43, 115001.
Alternate Names
B2L13; Bcl-2-like protein 13; Bcl-2L13; Bcl-rambo; BCL2 like 13; Bcl2-L-13; BCL2-like 13 (apoptosis facilitator); BCL2L13; MIL1; Protein Mil1
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