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CHGA (F7D6H) Rabbit Monoclonal Antibody #83651

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  • WB
  • IHC

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 80
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Simple Western™ 1:10 - 1:50
    IHC Leica Bond 1:500 - 1:2000
    Immunohistochemistry (Paraffin) 1:100 - 1:400

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    For a carrier free (BSA and azide free) version of this product see product #48041.

    Protocol

    Specificity / Sensitivity

    CHGA (F7D6H) Rabbit Monoclonal Antibody recognizes endogenous levels of total CHGA protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human CHGA protein.

    Background

    Chromogranin A (CHGA) and Chromogranin B (CHGB) are members of the chromogranin/secretogranin family of neuroendocrine secretory proteins. They reside in the secretory vesicles of neurons and endocrine cells and are debated to regulate cargo in the secretory pathway (1,2).
    CHGA is also useful as a serological and immunohistological marker for the presence of neuroendocrine tumors (NETs) from various tissue sources (3,4). CHGA may also be useful for the assessment of disease progression (5,6).

    Alternate Names

    AL-11; betagranin (N-terminal fragment of chromogranin A); Catestatin; CgA; CHGA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); Chromogranin-A; CMGA; EA-92; ER-37; ES-43; GE-25; GR-44; GV-19; LF-19; p-Glu serpinin precursor; Pancreastatin; parathyroid secretory protein 1; Pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14

    For Research Use Only. Not for Use in Diagnostic Procedures.
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