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CD1A (MTB1) Mouse Monoclonal Antibody #90916

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  • IHC

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa)
    Source/Isotype Mouse IgG1 kappa
    Application Key:
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    IHC Leica Bond 1:50
    Immunohistochemistry (Paraffin) 1:50

    Storage

    Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 6 months when stored at 4°C. Do not aliquot the antibody.

    Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation.

    Protocol

    Specificity / Sensitivity

    CD1A (MTB1) Mouse Monoclonal Antibody recognizes endogenous levels of CD1A protein. Non-specific staining was observed in testis by immunohistochemistry.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a prokaryotic recombinant fusion protein corresponding to the full external domain of human CD1A protein.

    Background

    CD1A is a type 1 cell surface transmembrane glycoprotein structurally similar to MHC Class 1 that is expressed in association with β2-microglobulin (1). CD1A is a member of the CD1 family and has been shown to mediate the presentation of primary lipid and glycolipid antigens to T cell lymphocytes for recognition (1,2). It is expressed by Langerhans’ cells, cortical double positive and single positive thymocytes, and by interdigitating dendritic cells (1). CD1A has been shown to identify T cell development (3).

    Alternate Names

    CD1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a; T6

    For Research Use Only. Not for Use in Diagnostic Procedures.
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