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ENPP6 (E7P2Q) Rabbit Monoclonal Antibody #95214

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  • WB

    Product Specifications

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 50
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    ENPP6 (E7P2Q) Rabbit Monoclonal Antibody recognizes endogenous levels of total ENPP6 protein.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro65 of mouse ENPP6 protein.

    Background

    Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) is a choline-specific glycerophosphodiesterase that belongs to the ENPP family. The seven ENPP family members play different biological roles in nucleotide and phospholipid signaling, bone mineralization, fibrotic diseases, and tumor-associated immune cell infiltration. ENPP6 is GPI-anchored to the plasma membrane and contains a PDE domain (1). This enzyme hydrolyzes polyunsaturated lysophosphatidylcholine (LPC), glycerophosphorylcholine (GPC), or sphingosylphosphorylcholine (SPC) in kidney and brain (2). It can be used as a marker of newly-forming oligodendrocytes in mouse brain (3). 

    Alternate Names

    4833421B01Rik; B830047L21Rik; Choline-specific glycerophosphodiester phosphodiesterase; D8Ertd514; D8Ertd514e; E-NPP 6; E-NPP6; ectonucleotide pyrophosphatase/phosphodiesterase 6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 soluble form; Enpp6; Glycerophosphocholine cholinephosphodiesterase ENPP6; GPC-Cpde; NPP-6; Npp6

    For Research Use Only. Not for Use in Diagnostic Procedures.
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