Docetaxel is supplied as 1 mg powder. Store at or below -20ºC. Before use, dissolve powder in 1 ml DMSO to make a 1 mg/ml stock solution. The suggested working concentration is 100 ng/ml in tissue culture medium. Treat cells for 4-24 hours. Store solution at -20ºC.
|Soluble in DMSO at 200mg/ml and EtOH at 100mg/ml.
Docetaxel belongs to the taxane family of antitumor and antileukemic agents (1). A microtubule-stabilizing agent, docetaxel acts as an inhibitor of cellular functions that require microtubule dynamics including cell division, and is now in use as a treatment for breast, prostate and lung cancer (2).
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