GIRK2 Antibodies

Target Information

This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily. Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas. Note: This description may include information from UniProtKB.

Alternate Names

BIR1; G protein-activated inward rectifier potassium channel 2; GIRK-2; GIRK2; hiGIRK2; Inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; IRK6; KATP-2; KATP2; KCNJ6; KCNJ7; KIR3.2; KPLBS; MGC126596; Potassium channel, inwardly rectifying subfamily J member 6; potassium channel, inwardly rectifying subfamily J, member 6; potassium inwardly rectifying channel subfamily J member 6; potassium inwardly-rectifying channel J6; potassium inwardly-rectifying channel, subfamily J, member 6; potassium voltage-gated channel subfamily J member 6